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Kava Botany How to read Kava chemotypes

Discussion in 'In-Depth Kava Discussion' started by aviavieu, Jul 27, 2019.

  1. aviavieu

    aviavieu Member

    How to perfectly learn to read Kava chemotypes? So that I know what profile of action Kava has ?
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  2. Intrepidus_dux

    Intrepidus_dux Kava Enthusiast

  3. Krunʞy

    Krunʞy . Admin

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  4. Pecorino

    Pecorino Member

    And here's some of my notes from back when I also looked into this so you have it in a nutshell.

    1. Desmethoxyangonin
    Desmethoxyyangonin. Role in increasing the dopamine levels considered by scientists.

    2. Dihydrokavain (DHK)
    Associated with the "heavy" kavas. Appears to contribute significantly to the anxiolytic effects of kava.

    3. Yangonin
    Proven association with cannabinoid receptors.

    4. Kavain
    Associated with the "heady" kavas. More studies available than for other kavalactones, yet still it's unclear how it works. Proven anxiolytic, psychoactive and analgesic effects.

    5. Dihydromethysticin (DHM)
    Associated with "heavy" kavas, claimed to have long-lasting effects, proven analgesic, anticonvulsant, and anxiolytic effects, may cause issues related to benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide.

    6. Methysticin
    May cause issues related to benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide.

    Typical chemotype description consists of six digits, representing the six major kavalactones. They're ordered by the contents: 321456 kava contains more yangonin than dihydrokavain, more dihydrokavain than desmethoxyangonin and so on. Digit 2 on the first position presumably indicates "heavy" kava. 46 as the start - very "heady".
  5. aviavieu

    aviavieu Member

    So in a nutshell
    Kavain-
    It works and adds euphoria

    Yangonin -
    stimulates, adds energy

    Dihydrokavain -
    It works sedately

    dihydromethysticin
    Theses work seditively, but it's good that this kavalactones is not too much, because it can cause drowsiness and other unpleasant effects


    how it works ?
    desmethoxyyangonin And Methysticic

    I can not find any information on the internet about their operation. I will be grateful for the answers or hints from the elaborations on the operation of these two Kavalactones
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  6. aviavieu

    aviavieu Member

    It only remains to find out how methysticin works
  7. Henry

    Henry . Moderator The Kava Society of New Zealand

    There are so many unknowns here that if you are looking for a simple answer, you will be disappointed. The above info provides some hints, but certainly not the whole answer. It is the equivalent of saying that "ethanol makes you brave" or "thc makes you happy".
    kasa_balavu and kastom_lif like this.
  8. Kavacoordinate

    Kavacoordinate Kava Enthusiast

    individual biochemistry will render any canned responses useless. everyone loved Kula when BKH had it. It was a typical heady Tongan, but did nothing for me. Talk to the same people about the same kavas and you'll get several responses. Read up on Nangol noble vs Numbawan or Hiwa vs Hanakapi'ai and you'll see. There is no consistent presentation depending on what you're looking for.