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Kava Research Master List of Kava Research Articles (Currently 607)

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’Apo' Aporosa, S. 2015. “The New Kava User: Diasporic Identity Formation in Reverse.” New Zealand Sociology 30 (4): 58–77.

(Apo) Aporosa, S., and Matt Tomlinson. 2014. “Kava Hangover and Gold-Standard Science.” Anthropologica 56 (1): 163–75. https://doi.org/10.1353/ant.2014.0014.

Abdel Jaleel, Gehad A., Dalia O. Saleh, and Sally A. El-Awdan. 2013. “Antihyperglycaemic Effect of Kava Kava (piper Methysticum) in Streptozotocin- Induced Diabetic Rats.” Der Pharmacia Lettre 5 (5): 104–10.

Abu, Nadiah, M. Nadeem Akhtar, Swee Keong Yeap, Kian Lam Lim, Wan Yong Ho, Aimi Jamil Zulfadli, Abdul Rahman Omar, Mohd Roslan Sulaiman, Mohd Puad Abdullah, and Noorjahan Banu Alitheen. 2014. “Flavokawain A Induces Apoptosis in MCF-7 and MDA-MB231 and Inhibits the Metastatic Process in Vitro.” PloS One 9 (10): e105244. https://doi.org/10.1371/journal.pone.0105244.

Abu, Nadiah, Wan Yong Ho, Swee Keong Yeap, M. Nadeem Akhtar, Mohd Puad Abdullah, Abdul Rahman Omar, and Noorjahan Banu Alitheen. 2013. “The Flavokawains: Uprising Medicinal Chalcones.” Cancer Cell International 13 (1): 102. https://doi.org/10.1186/1475-2867-13-102.

Abu, Nadiah, Nurul Elyani Mohamed, Swee Keong Yeap, Kian Lam Lim, M. Nadeem Akhtar, Aimi Jamil Zulfadli, Beh Boon Kee, Mohd Puad Abdullah, Abdul Rahman Omar, and Noorjahan Banu Alitheen. 2015. “In Vivo Antitumor and Antimetastatic Effects of Flavokawain B in 4T1 Breast Cancer Cell-Challenged Mice.” Drug Design, Development and Therapy 9 (March): 1401–17. https://doi.org/10.2147/DDDT.S67976.

Abu, Nadiah, Nurul Elyani Mohameda, Nirosha Tangarajoo, Swee Keong Yeap, M. Nadeem Akhtar, Mohd Puad Abdullah, Abdul Rahman Omar, and Noorjahan Banu Alitheen. 2015. “In Vitro Toxicity and in Vivo Immunomodulatory Effects of Flavokawain A and Flavokawain B in Balb/C Mice.” Natural Product Communications 10 (7): 1199–1202. https://doi.org/10.1177/1934578X1501000716.

Ambrose, W. 1991. “Manus, Mortars and the Kava Concoction.” https://www.semanticscholar.org/paper/097e6b89e9b9b7cd01a76f4f8bc07e300fbca9ca.

Amdidouche-Hussain’I, Didja, and Joel Levesque. 1997. “Selection of Kavalactones by Complexation of Kava Extract with C Yclodextrins.” Drug Development and Industrial Pharmacy 23 (12): 1223–26. https://doi.org/10.3109/03639049709146161.

Anke, J., S. Fu, and I. Ramzan. 2006. “Kavalactones Fail to Inhibit Alcohol Dehydrogenase in Vitro.” Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 13 (3): 192–95. https://doi.org/10.1016/j.phymed.2004.07.005.

Anke, Jennifer, and Iqbal Ramzan. 2004a. “Pharmacokinetic and Pharmacodynamic Drug Interactions with Kava (Piper Methysticum Forst. F.).” Journal of Ethnopharmacology 93 (2-3): 153–60. https://doi.org/10.1016/j.jep.2004.04.009.

Anke, Jennifer, and Iqqbal Ramzan. 2004b. “Kava Hepatotoxicity: Are We Any Closer to the Truth?” Planta Medica 70: 193–96. https://doi.org/10.1055/s-2004-815533.

Apo Aporosa, S. 2011. “Apososa S. ‘Apo’ - 2011 - Is Kava Alcohol The Myths and the Facts.pdf.” Pacific Health Dialog 17 (1): 157–64. https://pubmed.ncbi.nlm.nih.gov/23008981/.

Apo’Aporosa, S. 2015. “Yaqona (kava) as a Symbol of Cultural Identity.” S. ‘. Aporosa.

Aporosa, A. S. 2019. “Kava, the Devil, and the Snake: Pentecostal Iconoclasm in Contemporary Fiji.” University of Auckland.

Aporosa, Apo. 2019. “Australia’s Discussion of Kava Imports Reflects Lack of Cultural Understanding.” The Conversation, June 9, 2019. http://theconversation.com/australi...eflects-lack-of-cultural-understanding-115662.

Aporosa, Apo S., Martin Atkins, and Richard Brunton. 2020. “Kava Drinking in Traditional Settings: Towards Understanding Effects on Cognitive Function.” Human Psychopharmacology 35 (2): e2725. https://doi.org/10.1002/hup.2725.

Aporosa, S. 2017. “Understanding Cognitive Functions Related to Driving Following Kava (Piper Methysticum) Use at Traditional Consumption Volumes.” In British Association for Psychopharmacology Conference, A84–A84. SAGE Publications. https://researchcommons.waikato.ac.nz/handle/10289/11307.

———. 2018. “Improving Road Safety and Health: Understanding Kava’s Impact on Driver Fitness.” University of Waikato. https://researchcommons.waikato.ac.nz/handle/10289/12947.

———. 2019. “Cognitive Functions Associated with Consumption of Traditional Volumes of Kava (Piper Methysticum): A Feasibility Study.” In British Association for Psychopharmacology. researchcommons.waikato.ac.nz. https://researchcommons.waikato.ac.nz/handle/10289/12780.

Aporosa, S. Apo. 2019a. “Kava and Ethno-Cultural Identity in Oceania.” In The Palgrave Handbook of Ethnicity, edited by Steven Ratuva, 1–15. Singapore: Springer Singapore. https://doi.org/10.1007/978-981-13-0242-8_134-1.

———. 2019b. “De-Mythologizing and Re-Branding of Kava as the New ‘world Drug’ of Choice.” Drug Science, Policy and Law 5 (January): 2050324519876131. https://doi.org/10.1177/2050324519876131.

Aporosa, S. Apo, Martin Atkins, and Jess N. Leov. 2021. “Decolonising Quantitative Methods within a Pacific Research Space to Explore Cognitive Effects Following Kava Use.” Journal of Interdisciplinary Research 5 (1). https://doi.org/10.26021/10642.

Aporosa, S. ’apo'. 2014. “YAQONA (KAVA) AND EDUCATION IN FIJI:INVESTIGATING ‘CULTURAL COMPLEXITIES’FROM A POST-DEVELOPMENT PERSPECTIVE.”

Aporosa, S., and Jacinta Forde. 2019. “Māori and Kava: New Drug Fashion or Re-Engagement With’kawa'?” Pacific Dynamics 3 (1): 72–85. https://researchcommons.waikato.ac.nz/handle/10289/12952.

Aporosa, S. G. 2008. Yaqona (Kava) and Education in Fiji: A Clash of Cultures? VDM Verlag.

Ashraf-Khorassani, M., L. T. Taylor, and M. Martin. 1999. “Supercritical Fluid Extraction of Kava Lactones from Kava Root and Their Separation via Supercritical Fluid Chromatography.” Chromatographia 50: 287–92. https://doi.org/10.1007/BF02490830.

Backhaul, Cord, and Josef Krieglstein. 1992. “Extract of Kava ( Piper Methysticum) and Its Methysticin Constituents Protect Brain Tissue against Ischemic Damage in Rodents.” European Journal ~>~ Pharmacoloj, % 215: 265269.

Backleh, Marlène, Perihan Ekici, Günther Leupold, and Harun Parlar. 2003. “Quantitative Elimination of Flavokavines A and B from Kava Kava (Piper Methysticum G. Forst) by Isoelectric Focused Adsorptive Bubble Separation.” Die Naturwissenschaften 90 (8): 366–69. https://doi.org/10.1007/s00114-003-0440-5.

Baker, Jonathan D. 2011. “Tradition and Toxicity: Evidential Cultures in the Kava Safety Debate.” Social Studies of Science 41 (3): 361–84. https://doi.org/10.1177/0306312710395341.

———. 2012. “Pills, Potions, Products: Kava’s Transformations in New and Nontraditional Contexts.” The Contemporary Pacific 24 (2): 233–65. https://doi.org/10.1353/cp.2012.0026.

Balick, Michael J., and Roberta Lee. 2002. “Traditional Use of Sakau (kava) in Pohnpei: Lessons for Integrative Medicine.” Alternative Therapies in Health and Medicine 8 (4): 96–98. https://www.ncbi.nlm.nih.gov/pubmed/12126179.

Balick, Michael J & Lee, Robert A. 2009. “The Sacred Root.” In Ethnobotany of Pohnpei, 165–203. University of Hawaii Press.

Barguil, Yann, Erwan Choblet, Sébastien Warter, and Mohammed Nour. 2013. “Kava Ichthyosis: A Nitric Oxide Synthase Inhibition?” Annales de Toxicologie Analytique 25 (4): 165–68. https://doi.org/10.1051/ata/2014001.

Barnes, Joanne, Linda A. Anderson, and J. D. Phillipson. 2007. “Kava - Overview.” In Herbal Medicines, 389–402. 3rd Ed. Grayslake, IL: Pharmaceutical Press.

Bauer, Rudolf, Brigitte & Kopp, and A. Nahrstedt. 2003. “Relevant Hepatotoxic Effects of Kava Still Need to Be Proven: A Statement of the Society for Medicinal Plant Research.” Planta Medica 69 (11): 971–72. https://doi.org/10.1055/s-2003-45140.

Baum, S. S., R. Hill, and H. Rommelspacher. 1998. “Effect of Kava Extract and Individual Kavapyrones on Neurotransmitter Levels in the Nucleus Accumbens of Rats.” Progress in Neuro-Psychopharmacology & Biological Psychiatry 22 (7): 1105–20. https://doi.org/10.1016/s0278-5846(98)00062-1.

Becker, Matheus William, Emerson Matheus Silva Lourençone, Alexandre Formighieri De Mello, Aline Branco, Edison Moraes Rodrigues Filho, Celso Ronaldo Blatt, Carlos Augusto Mallmann, Maurício Schneider, Rita Catalina Aquino Caregnato, and Carine Raquel Blatt. 2019. “Liver Transplantation and the Use of KAVA: Case Report.” Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 56 (March): 21–26. https://doi.org/10.1016/j.phymed.2018.08.011.

Behl, Mamta, Abraham Nyska, Rajendra S. Chhabra, Gregory S. Travlos, Laurene M. Fomby, Barney R. Sparrow, Milton R. Hejtmancik, and Po C. Chan. 2011. “Liver Toxicity and Carcinogenicity in F344/N Rats and B6C3F1 Mice Exposed to Kava Kava.” Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association 49 (11): 2820–29. https://doi.org/10.1016/j.fct.2011.07.067.

Berry, Jonna, Ashley Gilbert, and Justin Grodnitzky. 2019. “Cases of Kava Impairment in Iowa Drivers.” Journal of Forensic Sciences 64 (6): 1943–49. https://doi.org/10.1111/1556-4029.14130.

BfArM. 2002. “Kava Removal.” http://lrd.spc.int/ahp-publications/doc_download/578-gr-cis-bfarm-kava-removal.

Bian, Tengfei, Pedro Corral, Yuzhi Wang, Jordy Botello, Rick Kingston, Tyler Daniels, Ramzi G. Salloum, et al. 2020. “Kava as a Clinical Nutrient: Promises and Challenges.” Nutrients 12 (10). https://doi.org/10.3390/nu12103044.

Bilia, Anna Rita, Sandra Gallon, and Franco F. Vincieri. 2002. “Kava-Kava and Anxiety: Growing Knowledge about the Efficacy and Safety.” Life Sciences 70 (22): 2581–97. https://doi.org/10.1016/s0024-3205(02)01555-2.

Bilia, Anna Rita, Luca Scalise, Maria Camilla Bergonzi, and Franco F. Vincieri. 2004. “Analysis of Kavalactones from Piper Methysticum (kava-Kava).” Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 812 (1-2): 203–14. https://doi.org/10.1016/j.jchromb.2004.07.038.

Bird, Gail. 2016. “Import Restrictions: Kava and Khat.” The Office of Drug Control. December 7, 2016. https://www.odc.gov.au/import-restrictions-kava-and-khat.

Boerner, R. J. 2001. “Kava Kava in the Treatment of Generalized Anxiety Disorder, Simple Phobia and Specific Social Phobia.” Phytotherapy Research: PTR 15 (7): 646–47. https://doi.org/10.1002/ptr.1006.

Boerner, R. J., H. Sommer, W. Berger, U. Kuhn, U. Schmidt, and M. Mannel. 2003. “Kava-Kava Extract LI 150 Is as Effective as Opipramol and Buspirone in Generalised Anxiety Disorder--an 8-Week Randomized, Double-Blind Multi-Centre Clinical Trial in 129 out-Patients.” Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 10 Suppl 4: 38–49. https://doi.org/10.1078/1433-187x-00309.

Boerner, Reinhard J., and Stephan Klement. 2004. “Attenuation of Neuroleptic-Induced Extrapyramidal Side Effects by Kava Special Extract WS 1490.” Wiener Medizinische Wochenschrift 154 (21-22): 508–10. https://doi.org/10.1007/s10354-004-0115-7.

Boonen, G., B. Ferger, K. Kuschinsky, and H. Häberleinl. 1998. “In Vivo Effects of the Kavapyrones (+)-Dihydromethysticin And(±)-Kavain on Dopamine, 3,4-Dihydroxyphenylacetic Acid, Serotonin and 5-Hydroxyindoleacetic Acid Levels in Striatal and Cortical Brain Regions.” Planta Medica 64: 507–10.

Boonen, Georg, and Hanns Hberlein. 1998. “Influence of Genuine Kavapyrone Enantiomerson the GABAA Binding Site.” Planta Medica 64: 504–6.

Botello, Jordy F., Pedro Corral, Tengfei Bian, and Chengguo Xing. 2020. “Kava and Its Kavalactones Inhibit Norepinephrine-Induced Intracellular Calcium Influx in Lung Cancer Cells.” Planta Med 86 (1): 26–31. https://doi.org/10.1055/a-1035-5183.

Brown, Amy C., Janet Onopa, Peter Holck, Pakieli Kaufusi, Derek Kabasawa, Winston J. Craig, Klaus Dragull, Arieh M. Levine, and Jonathan D. Baker. 2007. “Traditional Kava Beverage Consumption and Liver Function Tests in a Predominantly Tongan Population in Hawaii.” Clinical Toxicology 45 (5): 549–56. https://doi.org/10.1080/15563650701365875.

Butt, Julia. 2019. Kava Usage in Aboriginal and Pacific Islander Communities in Australia. National Drug Research Institute.

Cairney, Sheree, Alan R. Clough, Paul Maruff, Alex Collie, Bart J. Currie, and Jon Currie. 2003. “Saccade and Cognitive Function in Chronic Kava Users.” Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 28 (2): 389–96. https://doi.org/10.1038/sj.npp.1300052.

Cairney, Sheree, Paul Maruff, and Alan R. Clough. 2002. “The Neurobehavioural Effects of Kava.” The Australian and New Zealand Journal of Psychiatry 36 (5): 657–62. https://doi.org/10.1046/j.1440-1614.2002.01027.x.

Capasso, A., and L. Sorrentino. 2005. “Pharmacological Studies on the Sedative and Hypnotic Effect of Kava Kava and Passiflora Extracts Combination.” Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 12 (1-2): 39–45. https://doi.org/10.1016/j.phymed.2004.03.006.

Catchpole, O. J., N. B. Perry, B. M. T. da Silva, J. B. Grey, and B. M. Smallfield. 2002. “Supercritical Extraction of Herbs I: Saw Palmetto, St John’s Wort, Kava Root, and Echinacea.” The Journal of Supercritical Fluids 22 (2): 129–38. https://doi.org/10.1016/S0896-8446(01)00110-3.

Cawte, John. 1986. “Parameters of Kava Used as a Challenge to Alcohol.” The Australian and New Zealand Journal of Psychiatry 20 (1): 70–76. https://doi.org/10.3109/00048678609158867.

Celentano, Antonio, Andrew Tran, Claire Testa, Krishen Thayanantha, William Tan-Orders, Stephanie Tan, Mitali Syamal, Michael J. McCullough, and Tami Yap. 2019. “The Protective Effects of Kava (Piper Methysticum) Constituents in Cancers: A Systematic Review.” Journal of Oral Pathology & Medicine: Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 48 (7): 510–29. https://doi.org/10.1111/jop.12900.

Celentano, Antonio, Callisthenis Yiannis, Rita Paolini, Pangzhen Zhang, Camile S. Farah, Nicola Cirillo, Tami Yap, and Michael McCullough. 2020. “Kava Constituents Exert Selective Anticancer Effects in Oral Squamous Cell Carcinoma Cells in Vitro.” Scientific Reports 10 (1): 1–11. https://doi.org/10.1038/s41598-020-73058-4.

Chambers, Megan I., Amy M. Osborne, and Rabi A. Musah. 2019. “Rapid Detection and Validated Quantification of Psychoactive Compounds in Complex Plant Matrices by Direct Analysis in Real Time-High Resolution Mass Spectrometry - Application to ‘Kava’ Psychoactive Pepper Products.” Rapid Communications in Mass Spectrometry: RCM 33 (24): 1915–25. https://doi.org/10.1002/rcm.8532.

Chaurasiya, Narayan D., Francisco León, Yuanqing Ding, Isabel Gómez-Betancur, Dora Benjumea, Larry A. Walker, Stephen J. Cutler, and Babu L. Tekwani. 2017. “Interactions of Desmethoxyyangonin, a Secondary Metabolite from Renealmia Alpinia, with Human Monoamine Oxidase-A and Oxidase-B.” Evidence-Based Complementary and Alternative Medicine: eCAM 2017 (August): 4018724. https://doi.org/10.1155/2017/4018724.

Chou, Tsui-Wei, Jia-Hua Feng, Chi-Chang Huang, Ya-Wen Cheng, Shih-Chang Chien, Sheng-Yang Wang, and Lie-Fen Shyur. 2013. “A Plant Kavalactone Desmethoxyyangonin Prevents Inflammation and Fulminant Hepatitis in Mice.” PloS One 8 (10): e77626. https://doi.org/10.1371/journal.pone.0077626.

Chua, Han Chow, Emilie T. H. Christensen, Kirsten Hoestgaard-Jensen, Leonny Y. Hartiadi, Iqbal Ramzan, Anders A. Jensen, Nathan L. Absalom, and Mary Chebib. 2016. “Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism.” PloS One 11 (6): e0157700. https://doi.org/10.1371/journal.pone.0157700.

Clayton, Natasha P., Katsuhiko Yoshizawa, Grace E. Kissling, Leo T. Burka, Po-Chuen Chan, and Abraham Nyska. 2007. “Immunohistochemical Analysis of Expressions of Hepatic Cytochrome P450 in F344 Rats Following Oral Treatment with Kava Extract.” Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Fur Toxikologische Pathologie 58: 223–36. https://doi.org/10.1016/j.etp.2006.08.002.

Clouatre, Dallas L. 2004. “Kava Kava: Examining New Reports of Toxicity.” Toxicology Letters 150: 85–96. https://doi.org/10.1016/j.toxlet.2003.07.005.

Clough, A. R., S. P. Jacups, Z. Wang, C. B. Burns, R. S. Bailie, S. J. Cairney, A. Collie, T. Guyula, S. P. McDonald, and B. J. Currie. 2003. “Health Effects of Kava Use in an Eastern Arnhem Land Aboriginal Community.” Internal Medicine Journal 33 (8): 336–40. https://doi.org/10.1046/j.1444-0903.2003.00405.x.

Clough, A. R., K. Rowley, and K. O’Dea. 2004. “Kava Use, Dyslipidaemia and Biomarkers of Dietary Quality in Aboriginal People in Arnhem Land in the Northern Territory (NT), Australia.” European Journal of Clinical Nutrition 58 (7): 1090–93. https://doi.org/10.1038/sj.ejcn.1601921.

Clough, Alan. 2003. “Enough! Or Too Much. What Is ‘Excessive’ Kava Use in Arnhem Land?” Drug and Alcohol Review 22 (1): 43–51. https://doi.org/10.1080/0959523021000059820.

Clough, Alan R., Sheree Cairney, Paul Maruff, Chris B. Burns, and Bart J. Currie. 2001. “Possible Toxicity and Withdrawal Seizures in Aboriginal Kava Drinkers in Arnhem Land, (Australia).” South Pacific Journal of Psychology 13: 26–33. https://doi.org/10.1017/S025754340000033X.

Connell, John. 2007. “Towards Free Trade in the Pacific? The Genesis of the ‘Kava-Biscuit War’ between Fiji and Vanuatu.” Geographical Research 45 (1): 1–12. https://doi.org/10.1111/j.1745-5871.2007.00425.x.

Connor, K. M., J. R. Davidson, and L. E. Churchill. 2001. “Adverse-Effect Profile of Kava.” CNS Spectrums 6 (10): 848, 850–53. https://doi.org/10.1017/s109285290000167x.

Connor, K. M., and J. R. T. Davidson. 2002. “A Placebo-Controlled Study of Kava Kava in Generalized Anxiety Disorder.” International Clinical Psychopharmacology 17 (4): 185–88. https://doi.org/10.1097/00004850-200207000-00005.

Connor, Kathryn M., Victoria Payne, and Jonathan R. T. Davidson. 2006. “Kava in Generalized Anxiety Disorder: Three Placebo-Controlled Trials.” International Clinical Psychopharmacology 21 (5): 249–53. https://doi.org/10.1097/00004850-200609000-00001.

Costa, Willian Richardes, Lucas Rossi Sartori, and José C. Tavares Carvalho. 2010. “Study of In Vitro and In Vivo Extraction of Kavalactones of Pharmaceutical Form Containing Ground Plant Drug (Piper Methysticum G. Forster).” Latin American Journal of Pharmacy 29 (2): 289–92. https://www.academia.edu/download/49124391/Kavalactones_LAJP.pdf.

Côté, Cynthia S., Christine Kor, Jon Cohen, and Karine Auclair. 2004. “Composition and Biological Activity of Traditional and Commercial Kava Extracts.” Biochemical and Biophysical Research Communications 322 (1): 147–52. https://doi.org/10.1016/j.bbrc.2004.07.093.

Coulter, David, Tamayo Carmen Sotheeswaran Subramaniam, Catherine Ulbricht, and World Health Organization. 2007. “Assessment of the Risk of Hepatotoxicity with Kava Products.pdf.” World Health Organization.

Cox, Paul Alan, and Lisa O’Rourke. 1987. “Kava (Piper Methysticum, Piperaceae).” Economic Botany 41 (3): 452–54. http://www.jstor.org/stable/4254999.

D. Schmitz ,CL Zhang ,SS Chatterjee &U. Heinemann. 1995. “Effects of Methysticin on Three Different Models of Seizure like Events Studied in Rat Hippocampal and Entorhinal Cortex Slices.” Naunyn-Schmiedeberg’s Archives of Pharmacology 351: 348–55. https://doi.org/10.1007/BF00169074.

Dai, Jun-Qi, Yi-Gang Huang, and Ai-Na He. 2015. “Dihydromethysticin Kavalactone Induces Apoptosis in Osteosarcoma Cells through Modulation of PI3K/Akt Pathway, Disruption of Mitochondrial Membrane Potential and Inducing Cell Cycle Arrest.” International Journal of Clinical and Experimental Pathology 8 (5): 4356–66. https://www.ncbi.nlm.nih.gov/pubmed/26191127.

Danan, Gaby, and Rolf Teschke. 2015. “RUCAM in Drug and Herb Induced Liver Injury: The Update.” International Journal of Molecular Sciences 17 (1). https://doi.org/10.3390/ijms17010014.

Davies, L. P., C. A. Drew, P. Duffield, G. A. Johnston, and D. D. Jamieson. 1992. “Kava Pyrones and Resin: Studies on GABAA, GABAB and Benzodiazepine Binding Sites in Rodent Brain.” Pharmacology & Toxicology 71 (2): 120–26. https://doi.org/10.1111/j.1600-0773.1992.tb00530.x.

De Leo, V., A. la Marca, G. Morgante, D. Lanzetta, P. Florio, and F. Petraglia. 2001. “Evaluation of Combining Kava Extract with Hormone Replacement Therapy in the Treatment of Postmenopausal Anxiety.” Maturitas 39 (2): 185–88. https://doi.org/10.1016/s0378-5122(01)00197-9.

Denery, Judith R., Klaus Dragull, C. S. Tang, and Qing X. Li. 2004. “Pressurized Fluid Extraction of Carotenoids from Haematococcus Pluvialis and Dunaliella Salina and Kavalactones from Piper Methysticum.” Analytica Chimica Acta 501 (2): 175–81. https://doi.org/10.1016/j.aca.2003.09.026.

Denham, Alison, Michael McIntyre, and Julie Whitehouse. 2002. “Kava—the Unfolding Story: Report on a Work-in-Progress.” The Journal of Alternative and Complementary Medicine 8 (3): 237–63. https://doi.org/10.1089/10755530260127943.

Dentali, Steven J., Cristina Amarillas, Tyler Blythe, Paula N. Brown, Anton Bzhelyansky, Christine Fields, Holly E. Johnson, et al. 2018. “Standard Method Performance Requirements (SMPRs®) 2018.005: Determination of Kavalactones And/or Flavokavains from Kava (Piper Methysticum).” Journal of AOAC International 101 (4): 1256–60. https://doi.org/10.5740/jaoacint.smpr2018.005.

Department of Industry, Tourism and Trade. 2020. “KAVA MANAGEMENT ACT 1998.” https://legislation.nt.gov.au/Legislation/KAVA-MANAGEMENT-ACT-1998.

Dharmaratne, H. Ranjith W., N. P. Dhammika Nanayakkara, and Ikhlas A. Khan. 2002. “Kavalactones from Piper Methysticum, and Their 13C NMR Spectroscopic Analyses.” Phytochemistry 59 (4): 429–33. https://doi.org/10.1016/s0031-9422(01)00443-5.

Dietlein, G., and D. Schröder-Bernhardi. 2003. “Doctors’ Prescription Behaviour Regarding Dosage Recommendations for Preparations of Kava Extracts.” Pharmacoepidemiology and Drug Safety 12 (5): 417–21. https://doi.org/10.1002/pds.839.

Dinh, L. D., U. Simmen, K. B. Bueter, B. Bueter, K. Lundstrom, and W. Schaffner. 2001. “Interaction of Various Piper Methysticum Cultivars with CNS Receptors in Vitro.” Planta Medica 67 (4): 306–11. https://doi.org/10.1055/s-2001-14334.

DiSilvestro, Robert A., Wenyi Zhang, and David J. DiSilvestro. 2007. “Kava Feeding in Rats Does Not Cause Liver Injury nor Enhance Galactosamine-Induced Hepatitis.” Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association 45 (7): 1293–1300. https://doi.org/10.1016/j.fct.2007.01.015.

Einbond, L. S., A. Negrin, D. M. Kulakowski, H-A Wu, V. Antonetti, F. Jalees, W. Law, et al. 2017. “Traditional Preparations of Kava (Piper Methysticum) Inhibit the Growth of Human Colon Cancer Cells in Vitro.” Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 24 (January): 1–13. https://doi.org/10.1016/j.phymed.2016.11.002.

Ernst, E. 2007. “A Re-Evaluation of Kava (Piper Methysticum).” British Journal of Clinical Pharmacology 64 (4): 415–17. https://doi.org/10.1111/j.1365-2125.2007.02932.x.

Ernst, Edzard. 2002. “Second Thoughts about Kava.” The American Journal of Medicine 113 (4): 347–48. https://doi.org/10.1016/S0002-9343(02)01204-4.

Fehoko, E. 2013. “From Kava to Coffee: Tongan Young People in Auckland.” Mana Ngākau: Community Compassion Māori and. https://www.academia.edu/download/33781543/From_Kava_to_Coffee_Tongan_Young_People_in_Auckland.pdf.

Fehoko, E., I. Hafoka, and A. Tecun. 2021. “Holding Tightly onto Land and People During a Pandemic: Kava Pedagogies and Tertiary Learning Relationships in Vahaope.” Researchgate.net. https://www.researchgate.net/profil...ertiary-Learning-Relationships-in-Vahaope.pdf.

Feltenstein, Matt W., L. Corinne Lambdin, M. Ganzera, H. Ranjith, W. Dharmaratne, N. P. Dhammika Nanayakkara, Ikhlas A. Khan, and Kenneth J. Sufka. 2003. “Anxiolytic Properties of Piper Methysticum Extract Samples and Fractions in the Chick Social-Separation-Stress Procedure.” Phytotherapy Research: PTR 17 (3): 210–16. https://doi.org/10.1002/ptr.1107.

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Geier, F. P., and T. Konstantinowicz. 2004. “Kava Treatment in Patients with Anxiety.” Phytotherapy Research: PTR 18 (4): 297–300. https://doi.org/10.1002/ptr.1422.

Gendle, M. H., A. K. Stroman, and D. P. Mullin. 2011. “Effect of an Acute Dose of Crude Kava Root Extract on Problem Solving in Healthy Young Adults.” Australian Journal of Medical Herbalism 23 (4): 160–63. https://search.informit.org/doi/abs/10.3316/informit.858304482995950.

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Guo, Lei, Qiang Shi, Stacey Dial, Qingsu Xia, Nan Mei, Quan-Zhen Li, Po-Chuen Chan, and Peter Fu. 2010. “Gene Expression Profiling in Male B6C3F1 Mouse Livers Exposed to Kava Identifies--Changes in Drug Metabolizing Genes and Potential Mechanisms Linked to Kava Toxicity.” Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association 48 (2): 686–96. https://doi.org/10.1016/j.fct.2009.11.050.

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Gurley, Bill J., Ashley Swain, Martha A. Hubbard, D. Keith Williams, Gary Barone, Faith Hartsfield, Yudong Tong, Danielle J. Carrier, Shreekar Cheboyina, and Sunil K. Battu. 2008. “Clinical Assessment of CYP2D6-Mediated Herb-Drug Interactions in Humans: Effects of Milk Thistle, Black Cohosh, Goldenseal, Kava Kava, St. John’s Wort, and Echinacea.” Molecular Nutrition & Food Research 52 (7): 755–63. https://doi.org/10.1002/mnfr.200600300.

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Jandial, Danielle D., Lauren S. Krill, Lixia Chen, Chunli Wu, Yu Ke, Jun Xie, Bang H. Hoang, and Xiaolin Zi. 2017. “Induction of G2M Arrest by Flavokawain A, a Kava Chalcone, Increases the Responsiveness of HER2-Overexpressing Breast Cancer Cells to Herceptin.” Molecules 22 (3). https://doi.org/10.3390/molecules22030462.

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Krum, Bárbara Nunes, Catiuscia Molz de Freitas, Ana Paula Chiapinotto Ceretta, Caroline Pilecco Barbosa, Elizete de Moraes Reis, Rahisa Scussel, Emily da Silva Córneo, Ricardo Andrez Machado-de-Ávila, Aline Augusti Boligon, and Roselei Fachinetto. 2021. “Kava Decreases the Stereotyped Behavior Induced by Amphetamine in Mice.” Journal of Ethnopharmacology 265 (January): 113293. https://doi.org/10.1016/j.jep.2020.113293.

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Li, Juan, Lei Zheng, Mi Yan, Jing Wu, Yongqing Liu, Xiaona Tian, Wen Jiang, Lu Zhang, and Rongmei Wang. 2020. “Activity and Mechanism of Flavokawain A in Inhibiting P-Glycoprotein Expression in Paclitaxel Resistance of Lung Cancer.” Oncology Letters 19 (1): 379–87. https://doi.org/10.3892/ol.2019.11069.

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The Kap'n

The Groggy Kaptain (40g)
KavaForums Founder
2nd Half of the list.

Liu, Zhongbo, Xia Xu, Xuesen Li, Shuman Liu, Anne R. Simoneau, Feng He, Xue-Ru Wu, and Xiaolin Zi. 2013. “Kava Chalcone, Flavokawain A, Inhibits Urothelial Tumorigenesis in the UPII-SV40T Transgenic Mouse Model.” Cancer Prevention Research 6 (12): 1365–75. https://doi.org/10.1158/1940-6207.CAPR-13-0219.

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