@mrwaka Here's a discussion on GGT we had once, it's quite long, but if you're curious you'll probably find some good info within it. Perhaps not definitive answers though. I can't recall everything that was said in that thread, but you've probably read in this thread that my Alkaline Phosphatase has always been in range so far, as well as the common ALT, AST and bilirubin markers. GGT is never part of my blood panel, so I have no data there. I've been drinking large daily quantities of kava for many years.
Where there might be some kava related issue, is with elevated cholesterol or a kava related interference with cholesterol metabolization. Excess cholesterol or abnormal metabolism of cholesterol can create gallstones, the gallbladder is part of the liver system. Therefor, if kava can cause a cholesterol issue, and cholesterol issues can cause gallbladder issues, then the hepatic system might respond with elevated GGT for whatever reason. -- I am not a doctor.
Additionally, I took a DNA test last year and ran the raw DNA through an additional health analysis. One of the things it found with me, was a gene that's associated with an increased likelihood of having gallbladder issues. I've never been professionally diagnosed with gallstones, but over the years I've experienced pain with the same behavior, intensity and in the same location as what is described when I've read about "gall-attacks". I've had this experience both before I drank kava regularly and after I started drinking regularly.
So it would seem that this gene very well might be active in me, it's a pretty common gene...anyway...what I'm I'm getting at, is that maybe people with this gene are going to inherently be more susceptible to kava related cholesterol/gallbladder/ggt issues.