+1 regarding the possibilities of tossing and washing.
Now, there is no conclusive evidence of any adverse effects, and like Keeron mentioned, we all do consume root material even after straining anyways. That being said, I would submit that because of the extensive metabolization by our GI, there is the possibility of a different absorption pattern in a pharmacokinetic way, more root material to having the potential to have an allergic reaction to, more GI and dermopathic side effects, and possibly absorption differences ratio or amount of certain compounds, desirable or not.
Micronized or instant is definitely the way to go for people looking for a way around other prep methods, but it must be said that putting powder in our mouth and then trying to swallow it has the potential for causing asphyxiation, infection, pneumonia or other respiratory conditions even if we are careful (the aforementioned conditions have been reported in cases of tossing and washing various things). All it takes is a simple sneeze of hiccup (or simply tilting our head back of something silly like that) for potentially uncomfortable or dangerous effects.
I'd recommend for those tossing and washing to do it one of two things: either use "stir and chug", "shake and wash", etc or "reverse toss and wash" because it puts less of a potential stress on the pharynx, epiglottis and esophagus and reduces the potential for adverse reactions to tossing and washing.
"Stir and Chug", "Shake and Wash", etc is where you have a small little vial (like an old medicine bottle that has a sealable lid) and pour the powder and water into it and shake it up and then swallow it. Most of the time, you will need to add more water and repeat the process to get all the material down though it is definitely worth the extra 45 seconds.
There is also the "reverse" toss and wash where you put a swig of water in your mouth, then carefully pour the powder into your mouth and swish it around before swallowing. This also makes it much easier on the pharynx, epiglottis and esophagus.