From my very limited experience with Kava and excessive reading on the internet. Some websites will state that Dermo MAY be caused by a molecular change that results in an allergic response overtime. Some of us seem to be more sensitive to that change. I read somewhere that those with seasonal allergies maybe more prone to this. I am one of those people it seems, I have to take a Zyrtec daily for my baseline seasonal allergies. I will get a bit of a cough, runny nose, dry inner canthus(corner of eye) and itchy red eyes if I binge on Kava for a few days in a row. I do not get hives, etc. and if I ever did, that will put a stop to my Kava use. I have taken a few notes/steps to control my symptoms before they start showing up.
1: It seems to be worse if I do toss and wash, so I do NOT do toss and wash
2: If I use traditional methods and medium grind, I have to strain out ALL the maka (woody parts). I may lose some of the kava lactones, but I am a lightweight so I don't need much. Did I mention I have to strain out ALL the maka?
3: I prefer to use either GHK's micro as they remove the maka before micronizing the product. Other companies, that have a micro, do not do this that I am aware of. I stick with Chris's product for micro.
4: If I feel like my cash flow is good, I will pinch for some instant at any reputable noble only company. As stated before I am a light head so the cost/use ratios are not that bad for me.
5: That being said these steps will give me an extra day or two of Kava use without symptoms, but they will eventually return.
6: So I take a few days off to reset my system and I will take half a benadryl at night before I go on my Kava fast to knock things back until the weekend!
7: Weekend I repeat!
Seems what ever is causing my issues in primary in the makas and not so bad in the rest of the root and it seems some cultivars are worse than others (nene seems to cause me more problems even as a micro). Hopefully as time progresses I can be a bit more desensitized to kava allergy so that I can enjoy this more often, but I am happy if I can only have it on weekends. As long as I don't get full blown hives, I will be fine as I am. I got hives as a kid and I do not want to live through that again.
Hope this helps,
avahZ