Hey @Bert07. I love your posts, your insight, your passion for kava and your ability to start thought provoking and interesting threads. The avatar, well... :-D But ultimately I really don't care, and neither does Rookie, when it comes down to it, so let's hug this one out ok, buddy? I'd hate to not have you around here to start threads like this one.
The only other thing I'm aware of that has a Reverse Tolerance effect is MJ, as that usually takes at least one go before you feel anything. That was my experience with it. Second time was the charm. Kava took me a good two weeks of off and on skepticism and persistence before I hit paydirt, so there may be some commonalities between the two in terms of building enough up in your system for the full effect to arrive. There's some kava action at CB receptors in the gut, and brain, right?
I'd LOVE to know the bio-chemical mechanisms in play. Sadly whenever I start reading about organic chemistry, my eyes glaze over and my mind wanders and I think, "Man, there are some SMART people out here who get this stuff. Where's that MAD magazine I had lying around here??" :-D
The only other thing I'm aware of that has a Reverse Tolerance effect is MJ, as that usually takes at least one go before you feel anything. That was my experience with it. Second time was the charm. Kava took me a good two weeks of off and on skepticism and persistence before I hit paydirt, so there may be some commonalities between the two in terms of building enough up in your system for the full effect to arrive. There's some kava action at CB receptors in the gut, and brain, right?
I'd LOVE to know the bio-chemical mechanisms in play. Sadly whenever I start reading about organic chemistry, my eyes glaze over and my mind wanders and I think, "Man, there are some SMART people out here who get this stuff. Where's that MAD magazine I had lying around here??" :-D